Navigating round the mouse brain

2 08 2015

For Danielle‘s project, we need to localize the caudate-putamen and nucleus accumbens, and ideally become able to trace the area of the former from its very front edge right to its posterior margin so we can then estimate its whole volume for each mouse. (The nucleus accumbens we can’t do this for, as it’s impossible to see unless you stain for dopamine).

That’s meant a lot of getting familiar with mouse brain anatomy, helped by this lovely 3-d visualization tool.

I’m impressed at how big the caudate-putamen is in a mouse (‘striatum’ in the pic below), and also relieved at how simple its shape is compared to the ‘alien-in-your-brain’ weirdness of the human equivalent.

Screen Shot 2015-08-02 at 10.39.07 AM